Emergence of cytomegalovirus disease in patients receiving temozolomide: report of two cases and literature review.

نویسندگان

  • Yolanda Meije
  • Manuel Lizasoain
  • Ana García-Reyne
  • Pilar Martínez
  • Virginia Rodríguez
  • Francisco López-Medrano
  • Rafael San Juan
  • Antonio Lalueza
  • José María Aguado
چکیده

Temozolomide chemotherapy has become part of the therapy used to treat glioblastoma multiforme and refractory anaplastic astrocytoma. Temozolomide frequently produces profound lymphopenia. We report 2 cases of cytomegalovirus disease that occurred in patients receiving temozolomide therapy and review 4 additional cases reported in the literature. Narrow monitoring with cytomegalovirus antigenemia assay should be considered for recommendation.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 50 12  شماره 

صفحات  -

تاریخ انتشار 2010